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The number of active sites exposed on the surface of some nanozymes can be estimated by methods such as chemical adsorption, spectroscopy, and geometric estimation 75

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Treatment with SUN significantly increased heart weight, cardiac index, and cardiotoxicity enzymatic indices, as well as severe histopathological changes

In general, treatment can be stopped once a healthy body weight is achieved and maintained, however, weight regain is likely when medication is stopped due to the fact that obesity is a long-term chronic health condition

doi:10.2215/cjn.0000000700

You can find a list below: More research is needed to understand why these happen and identify the factors that can help predict what will happen specifically