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Tissues were obtained through the National Disease Research Interchange (Philadelphia, PA) with approval from the University of Pittsburgh Committee for Oversight of Research and Clinical Training Involving Decedents (CORID)

Where genetic testing shows the presence of COMT genetic polymorphism, it would stand to reason that the person could be suffering from a dopamine excess

Gould says

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Remove from heat and let cool slightly

Next, l-glutamic acid-2,3,3,4,4-d5 (98% assay, MS, Canada) was freshly dissolved in water at 3 g/mL as an internal standard and added into each sample