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[8] investigated insulin regulation of total, intracellular, and cell surface GHRs and receptor biosynthesis and turnover

Biosynthesis (its creation in the body, all body cells are capable of this) also requires magnesium and ATP, among others

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The AML molecular landscape was explored at multiple omic layers, including WGS (173 tumors, 140 normals), WES (173 tumors, 161 normals), RNA-seq (172 tumors), proteomics including PTMs (162 tumors), metabolomics (91 tumors) and lipidomics (96 tumors) (Supplementary Table 1)