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Exendin 939 directly binds to the TRPV1 channel To assess the direct interaction between exendin 939 and the TRPV1 channel, we conducted a protein binding assay using His-tagged exendin 939, which was able to pull down the TRPV1 channel (Fig

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The SmPCs for all GLP-1 receptor agonists advise caution in patients with a history of pancreatitis, though they are not absolutely contraindicated

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