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Characteristics of secondary, primary, and compensated hypogonadism in aging men: evidence from the European Male Ageing Study

Modulating mitochondrial quality control Mitophagy inducers By activating the AMPK, metformin instigates a signaling cascade that culminates in the phosphorylation of ULK1, thereby facilitating mitophagy [26]

Unlike traditional peptides, MOTS-c directly influences cellular metabolism by enhancing glucose uptake, increasing fatty acid oxidation, and supporting mitochondrial function

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Prolonged alcohol misuse can also contribute to mental health disorders like depression and anxiety