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Yes, hyperthyroidism can affect the skin in several ways: Hyperpigmentation (melasma): Hormonal shifts, such as increased ACTH, may lead to darker patches of skin Excess sweating and rashes: Heat rashes often appear in skin folds due to higher sweat production Pretibial myxedema: A rare condition where the skin on the shins or tops of the feet becomes red, thickened, and swollen Associated autoimmune conditions: People with Graves disease may also develop vitiligo (loss of skin pigment) or alopecia areata (patchy hair loss) Functional medicine treatment considers both the thyroid imbalance and its skin manifestations, helping reduce symptoms and improve overall wellbeing

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Autophagy regulates sex steroid hormone synthesis through lysosomal degradation of lipid droplets in human ovary and testis