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Differential diagnosis Differential diagnosis includes seborrheic keratosis, warts, VIN, melanoma, and basal cell carcinoma

doi: 10.1016/S0140-6736(21)01324-6 71 FrasJPDaviesMJRosenstockJPrez ManghiFCFernndez LandLBergmanBKet al

LPS triggers the release of pro-inflammatory cytokines (e.g., IL-1, IL-6, TNF-), which can cross the blood-brain barrier and activate microglia in the central nervous system [14, 24]

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