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2] encompass individuals under the age of 21 who exhibit a fever exceeding 38.0 C for a duration exceeding 24 h (with a median duration of four to six days), along with laboratory findings indicating inflammation and signs of severe clinical illness involving multiple organ systems (involving two or more systems, including cardiac, renal, respiratory, hematologic, gastrointestinal, dermatologic, or neurological) [3, 14]

The question now is long-term commitment to maintaining these results

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[5] Topical GHK-Cu is generally considered well tolerated, yet therapy should be avoided in individuals with a known hypersensitivity to copper peptides or any vehicle component