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The emergence of GLP-1 drugs demonstrated how reframing a fundamental biological process can give rise to an entirely new, multi-billion-dollar drug category

Lim J, Lawson GW, Nakamura BN, Ortiz L, Hur JA, Kavanagh TJ, Luderer U

CD36 is distinct from the transporters regulating the traffic of carnitine and acylcarnitines, since it handles the hydrophobic fatty acid molecules as such, thus not directly participating to the carnitine network

While gastrointestinal side effects like nausea and vomiting were more common, there was no increased risk of hypoglycemia, suicide, or pancreatitis, underscoring the safety of GLP-1 RAs in this population

The TB-500 benefits guide covers the full spectrum of research applications

doi: 10.1016/j.bbrc.2016.10.064