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External toxins and cellular inflammation are the common factors in all chronic disease

Genetic Predisposition for Cytokine Storm Cytokine storm - also known as cytokine release syndrome or hypercytokinemia - represents a life-threatening over activation of the immune system where pro-inflammatory cytokines flood the body, leading to widespread inflammation, tissue damage, organ failure, and potentially death

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Payen, VL et al

It activates gene expression pathways involved in collagen production, tissue regeneration, and hair follicle stimulation

Human leucocyte antigen (HLA)-C-specific KIRs can bind zinc, and chelating zinc reverses their inhibitory function, suggesting that zinc is essential for their activity