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Watson E, Jonker DM, Jacobsen LV, Ingwersen SH

In additional studies, rhesus macaques immunized with a chimpanzee adenovirus (ChAdOx1 MERS) expressing MERS-CoV S protein, a recombinant S-RBD protein or a synthetic MERS-CoV S DNA vaccine, had decreased infection and no enhanced lung pathology upon challenge 129,130,131

Additionally, the study included only female participants, which, while reducing biological and hormonal variability, limits the generalizability of the findings to male fibromyalgia patients

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Interestingly, when ghrelin is administered alone to cells coexpressing D1R and GHSR1a, no increase in cAMP accumulation is observed, while typical levels of Ca 2+ accumulation associated with GHSR1a activation occur (Jiang et al., 2006)

Human islet T cells are highly reactive to preproinsulin in type 1 diabetes