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Targeting HER2 (ERBB2) amplification identified by next-generation sequencing (NGS) in patients with advanced or metastatic solid tumors 17(1S), 2017

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The controls simultaneously received an equivolume of saline (5.0 ml/kg ip) or water only (12 ml/rat/day)

Additionally, patients must follow MAD for at least 3 months, with some continuing MAD for over 2 years

Cardiovascular Issues : Certain peptides have been associated with an increased risk of cardiovascular problems, including high blood pressure, heart palpitations, and increased cholesterol levels

Endocrine 2003;21:18596