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This combination may interact with chemotherapy medicines (like doxorubicin and cisplatin), aluminum-containing antacids (like maalox), estrogen-containing medications (like estradiol), protease inhibitors (like indinavir), statins (like atorvastatin) and anticoagulants (like warfarin)

The lipoate moiety docked within the catalytic pocket, proximal to the catalytic serine-141 and histidine-296 residues (Fig

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