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Patients were stratified by pre-index HbA1c 9% (poorly controlled) and HbA1c 9% for poor control [22]

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2024;19(1):e0296733

In the UUO model, gasdermin-induced NET formation promoted MMT in macrophages by inducing nuclear traslocation of p65 [109] and the production and release of T-cell chemokines CXCL9/10/11 thus facilitating the infiltration of cytotoxic CD8 + T cells, which produce granzyme B to mediate kidney fibrosis [110]