Any degradation of the peptide structure interferes with receptor binding affinity and duration of action, potentially resulting in suboptimal glycaemic control and reduced weight loss efficacy
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If changing the weekly injection day is necessary, ensure at least 48 hours between doses, as specified in the FDA prescribing information
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Gastrointestinal symptoms are the most common early side effects, with nausea affecting approximately 44% of patients, vomiting 24%, diarrhea 30%, and constipation 24% during dose escalation according to clinical trials
