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The study protocol was approved by the Independent Bioethics Committee for Scientific Research at the Medical University of Gdansk (NKBBN/354 201/2017) and registered in the ClinicalTrials.gov Registry (NCT05120011)
One single-base deletion was induced in exon3 of the GSTM2 (NM_008183.3) gene using the TALEN method
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For a detailed walkthrough, see our [switching from semaglutide to tirzepatide guide](/guides/switching-from-semaglutide-to-tirzepatide-complete-guide)
Moreover, together with MZB-related signature transcripts such as Cr2 and Ighm , Gclc was also upregulated in Gclc fl/fl MZB compared to FoB (Fig
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