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Its tough to say, so we definitely need more hard science to look at that in a more objective way, Spittler said

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For a healthy adult under 50 with normal stomach acid and a varied omnivorous diet, a standard tablet works fine

Vitamin B12 requires an intrinsic factor-mediated active transport for absorption, therefore, lack of or inhibition of intrinsic factor results in pernicious anemia

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After reconstitution with bacteriostatic water , most protocols recommend use within 28 days when refrigerated