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148 Studies have shown that serum iron levels are abnormally low in severe infections, but iron overload is high in pulmonary fibrotic tissue and the brain

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PMID 2716644

Worsening of Anemia B12 deficiency can make anemia in thalassemia patients even worse

For instance, berberine, a natural compound, downregulates the expression of SLC1A5 in Hep3B and BEL-7404 cells, inhibiting Gln uptake and consequently suppressing expansion of liver cancer cells and tumor progression in vivo (77)

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