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More serious risks include pancreatitis, gallbladder disease, acute kidney injury with dehydration, suicidal ideation, and potential thyroid C-cell tumors (observed in rodent studies, though human relevance remains uncertain)

[DOI] [PMC free article] [PubMed] [Google Scholar] 103.Holmquist E., Brantster A.L., Meltzer H.M., Jacobsson B., Barman M., Sengpiel V

Whether inhibiting pyroptosis or blocking apoptotic pathways exerts synergistic or antagonistic effects on ferroptosis remains unclear

doi: 10.1111/j.1469-7580.2005.00403.x 79 EberleJAMRichterPWidmayerPChubanovVGudermannTBreerH

Principal Investigator on ESKETINTRD3004: An Open-label, Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression.

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