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Bacteroides fragilis polysaccharide a ameliorates abnormal voriconazole metabolism accompanied with the inhibition of tlr4/nf-b pathway

It comprises renal glutaminase-1 (GLS-1) and hepatic glutaminase-2 (GLS-2)

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The metabolism of lipophilic nutrients follows a different absorption pathway through the membrane compared to polar nutrients, majorly due to the non-polarity of lipophilic compounds (94)

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Given the findings on histology, a drug-induced dermal hypersensitivity reaction was suspected and semaglutide was discontinued