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Degradation of glutathione leads primarily to its constituent amino acids (e.g., cysteine, glycine), which can subsequently be used for glutathione synthesis inside the cell
doi: 10.1080/19490976.2020.1862612 34
4A), leading to similar antioxidant potency in cells, resembling freshly prepared NAC stocks (Fig
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In the following section, we translate these mechanistic findings into clinical applications, evaluating emerging strategiesincluding ferroptosis inhibitors, iron chelation therapies, and biomarker-driven approachesdesigned to disrupt this pathological cycle and modify the progression of COPD
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