Because it's not just a lower A1C
Making it more difficult to breakdown for those living with MTHFR mutations
Preclinical studies provide mechanistic evidence for interactions between the gut microbiota and incretin biology, which could suggest potential relevance to GLP-1 RA response
Gastroparesis semaglutide symptoms include persistent, severe nausea, vomiting of undigested food, a profound feeling of fullness after only a few bites, and significant abdominal discomfort
In the over 2500 participants, who were assigned to the 5, 10, and 15 mg doses of tirzepatide and placebo, the percent weight changes were both statistically and clinically significant compared with placebo
Each provides a different piece of the puzzle, and together they paint a picture that is concerning enough to warrant attention but not alarming enough to discourage GLP-1 medication use entirely