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The newest GLP-1 drug, tirzepatide, was first approved in 2022 as Mounjaro for treatment of diabetes and later approved in 2024 as Zepbound for obesity

Abnormal activation of pathways or obstruction of autophagic flux may lead to functional imbalance

Following the inclusion of lcFAODs in NBS panels in many countries worldwide, the number of patients diagnosed has significantly increased and the clinical spectrum has expanded, necessitating new algorithms for choosing the optimal therapeutic strategy

A deregulation of the NAD + levels has been associated with metabolic diseases and aging-related diseases, including neurodegeneration, defective immune responses, and cancer

doi: 10.1186/s12883-020-01839-5 5

Exploring the multifunctional roles of quantum dots for unlocking the future of biology and medicine