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The medication is administered as a once-weekly injection, offering convenience for long-term use
Obstetr Gynecol Survey
In these circumstances, the pyruvate generated by the actions of mitochondrial malic enzyme comes from fumarate precursors such as glutamine
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Mechanistically, the incubation of hemin with thiols (GSH, NAC, cysteine, mercaptoethanol, and thioglycolic acid) provokes major spectrophotometric changes in hemin despite the presence of low-affinity binders in serum [222]
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