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6 The phase 2 monotherapy dose-finding trial by Lau and colleagues established that once-weekly cagrilintide up to 4.5 mg produced dose-dependent weight loss about 10.8% at the top dose over 26 weeks with a gastrointestinal side-effect profile (nausea and related symptoms) that is the clinical fingerprint of a gut-slowing, satiating mechanism

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Working Mechanism Epithalon works by interacting with an enzyme called telomerase

The investigators demonstrated an increased growth and progression of PanIN lesions compared to animals without CP at baseline 18

It is well-tolerated, extensively studied, and provides a strong foundation before adding more targeted peptides

Laboratory factors such as macro-B12 (immunoglobulin-bound B12) can cause spurious elevation on some assays