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In an osteoarthritis model, a single liraglutide injection decreased synovitis and pain sensitivity, without affecting body weight

In contrast, someone with a lower BMI might be carrying fat predominantly around the abdomen

Vegetarians, people with food allergies, and those following specific dietary patterns need GLP-1 friendly meals adapted to their needs

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Human TT thyroid C cells were unexpectedly less responsive to GLP-1 ( via a calcitonin-dependent pathway, but this hypothesis still needs to be explored further

GLP-1 medications may reduce baseline hunger, but they do not directly address impulsive eating, emotional triggers that induce binging, or the reward response often felt with certain foods