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Combination therapy for kidney disease in people with diabetes mellitus
Its very difficult, especially as your age
But in the short run, GI side effects like Nausea, vomiting, and diarrhea can leave you dehydrated, and dehydration can cause a temporary drop in kidney function that shows up as a rising creatinine and a falling eGFR
The rationale for combining them is mechanistic complementarity (different signaling pathways, both implicated in tissue repair) and clinical anecdote in the peptide-therapy community not formal head-to-head or combination-vs-monotherapy data
Despite this, payers remain conflicted on whether pharmaceutical treatment for obesity should be covered
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