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A separate study from the University of Oxford, published in early 2026, found that weight regain after stopping GLP-1 medications was approximately 0.3 kg per month faster than weight regain after ending behavioral weight loss programs alone

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In conclusion, the SURMOUNT-1 trial demonstrates that Tirzepatide leads to substantial and clinically meaningful weight loss, improvement in cardiometabolic health, and is generally well tolerated, highlighting its therapeutic potential for individuals living with obesity

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reviewed the neuroprotective role of Nrf2 in AD, with special emphasis on the role of GSK-3 in the Nrf2 pathway (Qu et al., 2020)