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Euglycemic ketoacidosis (EKA) is a relatively rare but serious complication linked to the use of SGLT-2 inhibitors and, less frequently, GLP-1 receptor agonists

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The precise mechanisms are still being elucidated, but research suggests that glucagon agonism in Retatrutide contributes to: Increased Energy Expenditure: By stimulating metabolism, it helps the body burn more calories

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Based on the viability profile in U2OS-GFP-LC3 cells (data not shown), three different concentrations, with the relative viability (compared to control) at the highest concentration 80%, were selected for SQSTM1/p62 assessment