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While this is a single case report and not necessarily generalizable, it underscores why thyroid monitoring during GLP-1 therapy is not optional, it is essential

ACSS1 is a mitochondrial matrix enzyme that is strongly expressed in the heart, skeletal muscle, and brown adipose tissue

For example, they trigger an increase in the size of the sebaceous glands, leading to an increase in skin surface oils

a 31% increase in a product of lipid oxidation (MDA) and a 447% increase in a product of protein oxidation (protein carbonyl)] 47

doi: 10.1016/0165-1781(93)90102-M 28 MiuraHOzakiNSawadaMIsobeKOhtaTNagatsuT