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We did not estimate a treatment-policy (all-exposed/intention-to-treat-like) effect, as this represents a different estimand and would require additional prespecified analytic assumptions to appropriately handle treatment modification and its potentially non-random occurrence in routine care

Hydroxytyrosol, which is found in extra virgin olive oil, can lower inflammation by stopping cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase from working (80)

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Side Effects You Should Know: Nausea or vomiting (in the beginning) Constipation or loose stools Loss of appetite Fatigue or dizziness Most symptoms are temporary and manageable with medical supervision

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AS skeletal involvement may cause stiffness and pain in the: spine neck hands chest hips jaw Chronic inflammation can cause bones to fuse together, restricting your ability to move