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Enhanced A clearance, achieved through the delivery of the LRP1 minigene to the BBB via viral vectors, has been shown to reduce the accumulation of A in the brain parenchyma and alleviate A pathology [19]

doi: 10.1371/journal.pone.0101004 15 CrazeMLCheungHJewaNCoimbraNDMSoriaDEl-AnsariRet al