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However, the direct vascular protective effects of GLP-1 RAs, including anti-inflammatory and endothelial actions, could theoretically operate independently of baseline metabolic status [31]

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Whereas the above-mentioned studies have addressed the relationship of cognitive integrity with baseline levels of GSH, to our knowledge, it has not been explored whether GSH is modulated (showing a decrease or increase) as a consequence of cognitive effort (active engagement in a cognitive process) or sustained cognitive effort (continued engagement during a prolonged period)