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Important safety considerations include a boxed warning regarding thyroid C-cell tumors observed in rodents (though the relevance to humans is unknown) and contraindications for patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

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Branded pens usually last 21 days at room temperature, while compounded vials often have a Beyond Use Date (BUD) that varies by pharmacy protocol