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The most frequently reported adverse events were gastrointestinal events, including nausea, vomiting, diarrhea, constipation, or abdominal pain, which affected 79.6% of participants in the cagrilintide-semaglutide group and 39.9% of those in the placebo group

This provides a solid rationale for considering a switch if maximizing weight loss is a key objective, particularly if results with semaglutide have plateaued

Diabetes Care 22(3):409412

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