METHOD DETAILS Antibodies and reagents Antibodies against the following proteins were used (See also Key Resource Table): Cell Signaling: FOXO1 (2880), FOXO4 (9472), Phospho-Ser15 p53 (9286), PUMA (4976), BIM (C3C5), Cleaved Caspase-3 (9661), Sigma: FOXO4 (HPA040232), Tubulin (clone B512
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Providers may prescribe cyanocobalamin, a human-made form of B12
Prevention of vitamin B12 deficiency in people who need more vitamin B12 than usual due to certain conditions (such as pregnancy, thyroid problems, liver or kidney problems)
Merder, E
Moreover, immune cells secrete immune factors or their metabolites, which also impact the occurrence of ferroptosis in target organs and tissues involved in autoimmune diseases