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McKenna contributed equally to this work

Inflammation, cardiovascular disease and cancer: moving toward predictive medicine

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In this structure, the GLP-1R ECD has rotated slightly relative to the peptide-bound structures, and W33 has moved 14 , closing the top of the small-molecule binding pocket

[DOI] [PMC free article] [PubMed] [Google Scholar] 159.Zechmann B., Muller M

Similarly, insulin injections failed to reduce circulating glucose levels in Bbs5 / mice (Figure 1M), resulting in a higher area under the curve (Figure 1N)