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Progress in biomarker, neuroimaging, and data-science, evolution and implementation of adaptive trial designs, and back-translation from clinical to molecular insights are accelerating the trajectory toward true and clinically effective disease modification

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GLP-1RAs also decrease postprandial triglyceride excursions by modulating gut chylomicron synthesis and secretion [61]

On the other hand, trazodone, especially when prescribed in low doses, can work as a sedative

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