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Int Immunopharmacol 109:108824 Zhu L, Gu P, Shen H (2019) Protective effects of berberine hydrochloride on DSS-induced ulcerative colitis in rats

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In human cosmetic trials, a GHK-Cu nano-lipid carrier applied twice daily for 8 weeks reduced wrinkle volume by approximately 55.8% versus a control serum and approximately 31.6% versus Matrixyl 3000, while wrinkle depth dropped roughly 32.8%

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The team concluded that these results point to an "antimutagenic effect," which they hypothesize could be the source of epitalon's geroprotective abilities