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Cell 181 , 271280.e8 (2020)

The FDA granted traditional approval to Leqembi (lecanemab) in July 2023 after the Phase 3 CLARITYAD trial demonstrated clinically meaningful slowing of decline

This is particularly beneficial for individuals with Type 2 diabetes, who often struggle with insulin resistance

Lets explore their distinctive differences

Biological consequences include induction of androgen-independent proliferation, apoptosis resistance, autophagy inhibition, metabolic reprogramming (glycolysis activation), oxidative stress regulation, epithelial-mesenchymal transition, invadopodia formation, lymphangiogenesis, and ultimately therapy resistance and metastasis

Ozempic and Wegovy are similar medications, but they contain another GLP-1 drug called semaglutide