Qi Q, Shen Q, Geng J, An W, Wu Q, Wang N, Zhang Y, Li X, Wang W, Yu C, Li L
PLoS ONE 15 , e0228104 (2020)
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developed galactose-tailored poly (lactide-co-glycolide) (PLGA) nanoparticles loaded with AP (AP-GAL-NPs) for active liver targeting to treat HCC and found that AP-GAL-NPs exhibited a better protective effect against HCC in rats evidenced by the significant reduction of nodule formation, downregulation of MMP-2 and MMP-9, and induction of apoptosis in the liver ( 2.2 Anthocyanidin (ACN) More than 600 different ACNs have been identified in vegetables, which is derived from twenty-three different aglycones classified according to the number and position of hydroxyl and methoxyl groups on the flavan nucleus