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The structure of CTL1 was the first of the SLC44 family to be determined and reveal a unique and, for a transporter, unusual arrangement of the 10 transmembrane helices (17)

GLP-1 medications slow gastric emptying, meaning food stays in your stomach longer (review of GLP-1 receptor agonists, NIH/PMC)

[1] Licensed pharmacological options in the UK include orlistat (available at BMI 30 kg/m, or 28 kg/m with weight-related risk factors) and semaglutide (available within specialist weight management services as per NICE TA875, with adjusted BMI thresholds for some ethnic groups)

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Scheper W, Hoozemans JJ

This increase in quantity may be a compensatory mechanism to compensate for functional deficits