doi: 10.2337/dc06-2375
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Xun Chen, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Open questions in the GHK-Cu field include the specific cellular targets responsible for the broad transcriptomic effects, the relationship between the copper-delivery role and the direct peptide-only effects (if any), the comparative biology of GHK-Cu and related copper-peptides in defined cellular contexts, and the translation of cell-culture and animal-model findings to clinical-research endpoints under controlled study conditions
High-quality human clinical trials are still lacking, and this peptide is not FDA-approved for any medical use
Yes, preclinical studies suggest that these peptides may reduce scar formation by promoting efficient tissue regeneration and collagen production, leading to smoother recovery