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This was followed by the development of human GLP-1 analogs like liraglutide, which incorporated fatty acid molecules to extend their half-life and allow for once-daily dosing [25]

This occurred in 22.9% of patients at 7.2 mg versus 6% at 2.4 mg and 0.5% on placebo

All treatments were carried out after 5 cycles and were performed in technical quadruplicates seeded in different quadrants of the imaging plate, so as to avoid position effects

doi:10.3389/fendo.2021.645563

However, the paracrine effects of delta cell secretion products are beyond the scope of this review

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