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To test this hypothesis, SJL/J mice (n=21) were subjected to experimental autoimmune encephalomyelitis (EAE), an animal model of MS

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Endogenous DHHC9 depletion by adenovirus-mediated shRNAs markedly blocked palmitoylation (Supplementary Fig

This reduction results in diminished intestinal REG3G (Regenerating Family Member 3 Gamma) expression and increased bacterial translocation to the liver, exacerbating liver inflammation [152]

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