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Clinical trials comparing patients who lost weight through GLP-1 therapy versus those who lost equivalent weight through diet alone found that GLP-1 recipients often maintained better blood pressure control, suggesting the medication provides direct cardiovascular effects beyond caloric reduction

71 Ser and 86 Ser were substituted in a single reaction using the oligos oSA1F and oSA1R (Table S1)

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These methodological limitations underscore the need for future research using longitudinal designs and more robust data collection methods to validate and expand upon the findings