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The glucagon-like peptide 1 analogue exendin-4 attenuates alcohol mediated behaviors in rodents

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Fibromyalgia rats given Semaglutide exhibited reduced pain, improved motor coordination, reduced depression, systemic inflammation and inflammation in the dorsal root ganglia

10.1016/j.jhazmat.2020.124489 J

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Other studies demonstrated that SIRT1 activation by the GLP-1 agonist exendin-4 treatment protects mice under a high fat diet condition (Lee et al., 2012) and attenuates palmitate-induced ER stress and mitochondrial dysfunction (Lee et al., 2014)