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Clearly, a distinct metabolic pattern between Asian ginseng and American ginseng is discovered by OPLS-DA with a panel of urinary characteristic metabolites

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It was only recognized in the late 1980s that desensitization of insulin secretion, which describes a state of decreased secretory responsiveness of -cell to the glucose stimuli, is a pathophysiological phenomenon of -cell function and not just an in vitro artifact 30