fda glp-1 compounding warning letters october 2025 Issues Warnings Against Illegal Marketing FDA issued 25 warning letters

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This reduction may compromise the liver's ability to manage oxidative stress and perform detoxification, potentially contributing to disease progression

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Common side effects can include injection-site reactions, upper respiratory infections, nausea, and fungal infections

These findings led to changes in clinical practice guidelines modern diabetes guidelines recommend GLP-1 agonists (or related drugs) for patients with type 2 diabetes who have cardiovascular risk, and even suggest using a GLP-1 RA prior to insulin in many cases due to their multiple benefits and weight loss advantage ( [10] ) ( [11] )

Consistency is key results appear with regular use over several weeks