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Participants are consuming too many calories based on expert energy requirements, and too much sodium and saturated fat

The full cascade of benefits from optimized GH levels takes time to manifest because cellular repair and metabolic adjustments accumulate gradually

Excessive generation of reactive oxygen species activates redox-sensitive signalling pathways, including NF-B, leading to sustained release of pro-inflammatory cytokines such as TNF-, IL-6, and IL-1, which impair fibroblast function, collagen synthesis, and neovascularisation

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